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At the start of the epidemic more than 30 years ago, people who were diagnosed with HIV/AIDS could expect to live only 1-2 years after that diagnosis. This meant that the issues of aging were not a major focus for people with HIV disease.

But today, thanks to improvements in the effectiveness antiretroviral therapy (ART), people with HIV who are diagnosed early in their infection, and who get and stay on ART can keep the virus suppressed and live as long as their HIV-negative peers. For this reason, a growing number of people living with HIV in the United States are aged 55 and older. Many of them have been living with HIV for years; others are recently infected or diagnosed. According to CDC, people aged 55 and older accounted for more than one-quarter (26% or 313,2000) of the estimated 1.2 million people living with HIV in the U.S. in 2011.


So the good news is that people with HIV are living longer, healthier lives if they are on treatment and achieve and maintain a suppressed viral load. However, with this longer life expectancy Individuals living with long-term HIV infection exhibit many clinical characteristics commonly observed in aging: multiple chronic diseases or conditions, the use of multiple medications, changes in physical and cognitive abilities, and increased vulnerability to stressors.


While effective HIV treatments have decreased the likelihood of AIDS-defining illnesses among people aging with HIV, HIV-associated non-AIDS conditions are more common in individuals with long-standing HIV infection. These conditions include cardiovascular disease, lung disease, certain cancers, HIV-Associated Neurocognitive Disorders (HAND), and liver disease (including hepatitis B and hepatitis C), among others.

In addition, HIV appears to increase the risk for several age-associated diseases as well as to cause chronic inflammation throughout the body. Chronic inflammation is associated with a number of health conditions, includingcardiovascular disease, lymphoma, and type 2 diabetes. Researchers are working to better understand what causes chronic inflammation, even when people are being treated with ART for their HIV disease.  

HIV and its treatment can also have profound effects on the brain. Although AIDS-related dementia, once relatively common among people with HIV, is now rare, researchers estimate that more than 50 percent of people with HIV have an HIV-Associated Neurocognitive Disorder (HAND). HAND may include deficits in attention, language, motor skills, memory, and other aspects of cognitive function that may significantly affect a person’s quality of life. People who have HAND may also experience depression or psychological distress. Researchers are studying how HIV and its treatment affect the brain, including the affects on older people living with HIV.

For more information, see the National Institute on Aging’s Aging with HIV: Responding to an Emerging Challenge.




Older Americans are more likely than younger Americans to be diagnosed with HIV infection late in the course of their disease, meaning they get a late start to treatment and possibly more damage to their immune system. This can lead to poorer prognoses and shorter survival after an HIV diagnosis. Late diagnoses can occur because health care providers may not always test older people for HIV infection, and older people may mistake HIV symptoms for those of normal aging and don’t consider HIV as a cause.


Living with HIV presents certain challenges, no matter what your age. But older people with HIV may face different issues than their younger counterparts, including greater social isolation and loneliness. Stigma is also a particular concern among older people with HIV. Stigma negatively affects people’s quality of life, self-image, and behaviors, and may prevent them disclosing their HIV status or seeking HIV care.

Therefore, it is important for older people with HIV to get linked to HIV care and have access to mental health and other support services to help them stay healthy and remain engaged in HIV care. You can find support services through your healthcare provider, your local community center, or HIV/AIDS service organization. Or use the HIV Testing and Care Services Locator to find services near you.

Read their new blog: Spotlight on HIV and Aging



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